mRNA features

• Exon

  • Initial, internal, terminal
    • Codon usage, preference
    • Control elements (e.g. splice enhancers)

• Intron

  • 5� splice site (�GT�), branchpoint (lariat), 3� splice site (�AG�)
  • Repeat elements

• Start codon (translation start site)

  • �Kozak� rule

• UTR (untranslated regions)

  • 5� UTR
    • Translation regulatory elements
    • RNA binding sites
  • Initial, internal, terminal
    • Control elements (e.g. splice enhancers)
  • 3� UTR
    • RNA binding sites (cis-acting elements)

• Stop codon

• Poly-adenylation signal and site

• RNA destabilization signal

Previous slide

Next slide

Back to first slide

View graphic version