EST/cDNA alignment

• Sim4

  • Aligns cDNA to genomic sequence
  • Uses local similarity
  • Florea et al. (1998), Genome Research, 8, 967-974.

• GeneWise

  • Dynamic programming
  • Partial genes allowed
  • Based on Pfam and statistical splice site models
  • Birney (1999), unpublished
  • http://www.sanger.ac.uk/Software/Wise2

Previous slide

Next slide

Back to first slide

View graphic version