Genie: Gene Finder Based on Generalized Hidden Markov Models


Genie was a collaborative project involving the Computational Biology Group at the University of California, Santa Cruz, the Human Genome Informatics Group at the Lawrence Berkeley National Laboratory and the Berkeley Drosophila Genome Project. The main authors of Genie are David Kulp and Martin Reese.

Genie references:

  1. D. Kulp, D. Haussler, M.G. Reese, and F.H. Eeckman (1996). A generalized Hidden Markov Model for the recognition of human genes in DNA. ISMB-96, St. Louis, MO, AAAI/MIT Press.

  2. M.G. Reese, F.H. Eeckman, D. Kulp, D. Haussler (1997). Improved splice site detection in Genie. Proceedings of the First Annual International Conference on Computational Molecular Biology (RECOMB) 1997, Santa Fe, NM, ACM Press, New York.